From MM&M: "Study hammers last nail in the coffin for Bayer's Trasylol," by Ben Comer--
New study findings caused Bayer to begin withdrawing supplies of its antifibrinolytic drug, Trasylol (aprotinin injection), from the US market. Trasylol marketing efforts were suspended by the FDA, in November 2007, after preliminary study results suggested increases in the risk of death in patients, compared with two other drugs used to control bleeding, the FDA said in a statement.
The study, Blood conservation using antifibrinolytics: A randomized trial in a cardiac surgery population (dubbed BART), was published in the New England Journal of Medicine (NEJM). According to NEJM, the study found aprotinin to be the most effective hemostatic agent in comparison with lysine analogues. However, “at 30 days, patients who were receiving aprotinin in BART had an increased risk of death of more than 50% ... an outcome that led trial investigators to conclude that aprotinin should no longer be used in patients undergoing high-risk cardiac surgery.”
--Posted by St. Louis personal injury lawyers and attorneys and the Missouri accident attorneys of Schaeffer & Lamere, P.C., handling car accident, truck accidents, personal injury, pharmaceutical cases, products liability injuries, workers' compensation, medical malpractice, truck accidents, and all other types of injury cases.